SynerG™ — Joint Preservation Program | Dr. Frank McCormick
Joint Preservation Program

Avoid replacement.
Preserve your active life.

SynerG™ combines advanced PRP, A2M, BMAC, objective outcomes tracking, and physician-led rehabilitation to help appropriate patients stay active longer.

Developed by Harvard-trained orthopedic surgeon Dr. Frank McCormick.

Harvard-trained orthopedic surgeon
Over 5,000 orthopedic procedures performed
Outcomes tracked using the SIGMA Scoreboard™

See if you're a candidate

Complete the short form and our team will follow up about next steps.

About Dr. McCormick

Why patients choose SynerG™

Physician-led joint preservation at SynerG

Most regenerative medicine programs offer a single injection. SynerG™ was designed to offer something more: a comprehensive, physician-led joint preservation system focused on improving joint health, reducing pain, restoring function, and helping patients stay active longer.

Led by Dr. Frank McCormick, a board-certified orthopedic sports medicine surgeon and nationally recognized expert in joint preservation, SynerG™ combines advanced biologic therapies with objective measurement, personalized coaching, and continuous outcome tracking.

Rather than treating a single symptom, SynerG™ evaluates the entire joint ecosystem and creates a personalized roadmap for recovery — helping patients move better, feel better, and potentially delay or avoid more invasive procedures whenever appropriate.

The integrated approach

Precision. Measurement. Optimization.

Every treatment begins with understanding where your joint is today — and where it can go tomorrow.

01 — PRP

High-quality Platelet-Rich Plasma

Supports the body's natural healing response, delivered with precision.

02 — JOINT AGE™

Joint Age™ Assessment

A proprietary framework evaluating symptoms, function, imaging, exam findings, biomarkers, and recovery potential to quantify joint health.

03 — A2M

Alpha-2-Macroglobulin

Helps protect cartilage and support a healthier joint environment.

04 — 100 DAYS

100 Days to Health™

A structured recovery program built around nutrition, exercise, mobility, and lifestyle to maximize results.

05 — SIGMA™

SIGMA™ Outcome Tracking

Objective measurement and continuous process improvement to monitor progress over time.

— GOAL

A personalized roadmap

Designed to help you move better, feel better, and stay active longer.

Excellence defined by outcomes

The future of joint preservation

Through objective data, advanced biologics, and physician-guided optimization — a more comprehensive, measurable approach to joint preservation.

"Excellence Defined by Outcomes. Powered by Precision."

The SynerG™ Difference

Built differently — a system, not an injection

Developed by Dr. Frank McCormick, SynerG™ combines advanced biologic therapies — PRP, A2M, and BMAC — with objective measurement, personalized recovery optimization, and continuous outcome tracking.

Using our proprietary Joint Age™ assessment and 100 Days to Health™ program, we evaluate not only the condition of your joint, but your body's ability to heal, recover, and perform at its highest level.

Free download

"Joint preservation is more than an injection. It's a system."

Download the SynerG™ Joint Preservation Guide and learn how Joint Age™, PRP, A2M, BMAC, and the 100 Days to Health™ framework work together into a personalized strategy.

SynerG Joint Preservation Guide
The SynerG™ model

Precision-engineered for joint regeneration

A complete joint preservation protocol — not just a single injection.

DIAGNOSIS

Precision orthopedic diagnosis

Advanced imaging review and surgeon evaluation to confirm candidacy and map the treatment plan.

PRP

Regenerative signaling

Platelet-rich plasma delivered under ultrasound guidance to stimulate the joint's natural repair response.

A2M

Protease protection

Alpha-2-macroglobulin neutralizes destructive enzymes that accelerate cartilage breakdown.

BMAC

Cellular augmentation

Bone marrow aspirate concentrate provides mesenchymal stem cells for deeper tissue repair when indicated.

Candidacy

Is SynerG™ right for you?

Designed for patients with mild to moderate arthritis who want to stay active — not those requiring immediate joint replacement.

You may be a candidate

  • Mild to moderate knee or hip arthritis
  • Want to delay or avoid joint replacement
  • Persistent pain despite PT, injections, or meds
  • Want to stay active in sports, work, or family life

May not be a candidate

  • Severe end-stage arthritis
  • Major deformity or instability
  • Active joint infection
  • Joint damage too advanced for preservation
How we compare

SynerG™ vs. a typical PRP clinic

FeatureTypical PRP clinicSynerG™
Orthopedic surgeon evaluationVariableYes
Advanced imaging reviewVariableYes
Ultrasound-guided treatmentVariableYes
PRP, BMAC, and A2M optionsLimitedYes
Physical therapy integrationRareYes
Outcome trackingRareYes
Surgical expertise if neededRareYes
Complete joint preservation planRareYes
Limited Enrollment

Only a limited number of patients are accepted each month

Knee arthritisHip arthritisJoint preservation candidates

Because every patient undergoes a detailed candidacy evaluation and outcome tracking process, availability is intentionally limited.

Patient stories

Real Patients. Real Progress.

Hear directly from patients who chose joint preservation with SynerG™.

FAQ

Common questions

Does insurance cover SynerG™?+

Many orthobiologic treatments are considered self-pay. Our team will review your options before treatment.

How much does treatment cost?+

Treatment cost depends on the joint, severity, and biologic treatment plan. Financing options may be available.

Is SynerG™ the same as stem cell therapy?+

SynerG™ may include platelet-rich plasma, bone marrow aspirate concentrate, A2M, and rehabilitation depending on the patient's needs.

Can SynerG™ help me avoid surgery?+

For appropriate patients, SynerG™ is designed to help preserve the joint, reduce pain, and delay or potentially avoid joint replacement.

How do I know if I'm a candidate?+

A consultation, exam, and imaging review are required to determine candidacy. We do not accept every patient — every candidate undergoes physician review.